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Location and dynamic changes of inflammation, fibrosis, and expression levels of related genes in SiO(2)-induced pulmonary fibrosis in rats in vivo
Silicosis is a serious occupational disease characterized by pulmonary fibrosis, and its mechanism and progression have not been fully elucidated yet. In this study, silicosis models of rat were established by a one-time dusting method, and the rats were sacrificed after 30, 60, and 120 days (herein...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831492/ https://www.ncbi.nlm.nih.gov/pubmed/31719752 http://dx.doi.org/10.1293/tox.2019-0024 |