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Immunohistochemical characterization of oxidative stress in the lungs of rats exposed to the humidifier disinfectant polyhexamethylene guanidine hydrochloride

Polyhexamethylene guanidine hydrochloride (PHMG-HCl), an antimicrobial additive in humidifier disinfectants, was associated with the pulmonary disease outbreak in South Korea. However, PHMG-mediated oxidative stress has only been studied in vitro. Here, we evaluated PHMG-induced oxidative stress in...

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Detalles Bibliográficos
Autores principales: Lee, Yong-Hoon, Seo, Dong-Seok, Lee, Mi Ju, Cha, Hyo-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831495/
https://www.ncbi.nlm.nih.gov/pubmed/31719760
http://dx.doi.org/10.1293/tox.2019-0049