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Renal lesions in leptin receptor-deficient medaka (Oryzias latipes)

The aim of this study was to elucidate the renal lesions of leptin receptor-deficient medaka showing hyperglycemia and hypoinsulinemia and to evaluate the usefulness of the medaka as a model of diabetic nephropathy. Leptin receptor-deficient medaka at 20 and 30 weeks of age showed hyperglycemia and...

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Detalles Bibliográficos
Autores principales: Chisada, Shinichi, Sugiyama, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831499/
https://www.ncbi.nlm.nih.gov/pubmed/31719758
http://dx.doi.org/10.1293/tox.2019-0021