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Silencing of the foot-and-mouth disease virus internal ribosomal entry site by targeting relatively conserved region among serotypes

Foot-and-mouth disease (FMD) is a host-restricted disease of cloven-hoofed animals, such as cattle and pigs. There are seven major serotypes of FMD virus that exhibit high antigenic variation, making vaccine strain selection difficult. However, there is an internal ribosomal entry site (IRES) elemen...

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Detalles Bibliográficos
Autores principales: Matsui, Takafumi, Handa, Yoshio, Kanda, Takehiro, Tsukiyama-Kohara, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831537/
https://www.ncbi.nlm.nih.gov/pubmed/31367998
http://dx.doi.org/10.1007/s11262-019-01696-6