Ablation of RIP3 protects from dopaminergic neurodegeneration in experimental Parkinson’s disease

Parkinson’s disease (PD) is driven by dopaminergic neurodegeneration in the substantia nigra pars compacta (SN) and striatum. Although apoptosis is considered the main neurodegenerative mechanism, other cell death pathways may be involved. In this regard, necroptosis is a regulated form of cell deat...

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Detalles Bibliográficos
Autores principales: Dionísio, Pedro A., Oliveira, Sara R., Gaspar, Maria M., Gama, Maria J., Castro-Caldas, Margarida, Amaral, Joana D., Rodrigues, Cecilia M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831575/
https://www.ncbi.nlm.nih.gov/pubmed/31690718
http://dx.doi.org/10.1038/s41419-019-2078-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831575/
https://www.ncbi.nlm.nih.gov/pubmed/31690718
http://dx.doi.org/10.1038/s41419-019-2078-z

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