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Ablation of RIP3 protects from dopaminergic neurodegeneration in experimental Parkinson’s disease
Parkinson’s disease (PD) is driven by dopaminergic neurodegeneration in the substantia nigra pars compacta (SN) and striatum. Although apoptosis is considered the main neurodegenerative mechanism, other cell death pathways may be involved. In this regard, necroptosis is a regulated form of cell deat...
Autores principales: | Dionísio, Pedro A., Oliveira, Sara R., Gaspar, Maria M., Gama, Maria J., Castro-Caldas, Margarida, Amaral, Joana D., Rodrigues, Cecilia M. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831575/ https://www.ncbi.nlm.nih.gov/pubmed/31690718 http://dx.doi.org/10.1038/s41419-019-2078-z |
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