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Steady-state activation of the high-affinity isoform of the α4β2δ GABA(A) receptor

Activation of GABA(A) receptors consisting of α4, β2 (or β3), and δ subunits is a major contributor to tonic inhibition in several brain regions. The goal of this study was to analyze the function of the α4β2δ receptor in the presence of GABA and other endogenous and clinical activators and modulato...

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Detalles Bibliográficos
Autores principales: Pierce, Spencer R., Senneff, Thomas C., Germann, Allison L., Akk, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831628/
https://www.ncbi.nlm.nih.gov/pubmed/31690811
http://dx.doi.org/10.1038/s41598-019-52573-z