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Method and its Composition for encapsulation, stabilization, and delivery of siRNA in Anionic polymeric nanoplex: An In vitro- In vivo Assessment

Small interfering RNA (siRNA) are synthetic RNA duplex designed to specifically knockdown the abnormal gene to treat a disease at cellular and molecular levels. In spite of their high potency, specificity, and therapeutic potential, the full-fledged utility of siRNA is predominantly limited to in vi...

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Detalles Bibliográficos
Autores principales: Raval, Nidhi, Jogi, Hardi, Gondaliya, Piyush, Kalia, Kiran, Tekade, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831632/
https://www.ncbi.nlm.nih.gov/pubmed/31690769
http://dx.doi.org/10.1038/s41598-019-52390-4