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D-Ribose Induces Podocyte NLRP3 Inflammasome Activation and Glomerular Injury via AGEs/RAGE Pathway

D-ribose levels are demonstrated to be increased in type II diabetes mellitus and increased blood D-ribose is involved in the development of diabetic complications such as diabetic encephalopathy and nephropathy. However, the mechanism mediating the pathogenic role of D-ribose in nephropathy remains...

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Detalles Bibliográficos
Autores principales: Hong, Jinni, Li, Guangbi, Zhang, Qinghua, Ritter, Joseph, Li, Weiwei, Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831643/
https://www.ncbi.nlm.nih.gov/pubmed/31737627
http://dx.doi.org/10.3389/fcell.2019.00259