Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders

In a previous study, we proposed that age-related mitochondrial respiration defects observed in elderly subjects are partially due to age-associated downregulation of nuclear-encoded genes, including serine hydroxymethyltransferase 2 (SHMT2), which is involved in mitochondrial one-carbon (1C) metabo...

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Detalles Bibliográficos
Autores principales: Tani, Haruna, Mito, Takayuki, Velagapudi, Vidya, Ishikawa, Kaori, Umehara, Moe, Nakada, Kazuto, Suomalainen, Anu, Hayashi, Jun-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831688/
https://www.ncbi.nlm.nih.gov/pubmed/31690790
http://dx.doi.org/10.1038/s41598-019-52372-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831688/
https://www.ncbi.nlm.nih.gov/pubmed/31690790
http://dx.doi.org/10.1038/s41598-019-52372-6

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