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Increased Hemoglobin Oxygen Affinity With 5-Hydroxymethylfurfural Supports Cardiac Function During Severe Hypoxia

Acclimatization to hypoxia or high altitude involves physiological adaptation processes, to influence oxygen (O(2)) transport and utilization. Several natural products, including aromatic aldehydes and isothiocyanates stabilize the R-state of hemoglobin (Hb), increasing Hb-O(2) affinity and Hb-O(2)...

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Detalles Bibliográficos
Autores principales: Lucas, Alfredo, Ao-ieong, Eilleen S. Y., Williams, Alexander T., Jani, Vivek P., Muller, Cynthia R., Yalcin, Ozlem, Cabrales, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831744/
https://www.ncbi.nlm.nih.gov/pubmed/31736778
http://dx.doi.org/10.3389/fphys.2019.01350