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Metformin induces lipid changes on sphingolipid species and oxidized lipids in polycystic ovary syndrome women

Metformin is one of the treatments used for PCOS pathology decreasing body weight, plasma androgen, FSH and glucose levels. Unfortunately, there is little known about metformin’s effects on lipid metabolism, a crucial process in PCOS pathology. We have employed a lipidomic approach to explore altera...

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Detalles Bibliográficos
Autores principales: Pradas, Irene, Rovira-Llopis, Susana, Naudí, Alba, Bañuls, Celia, Rocha, Milagros, Hernandez-Mijares, Antonio, Pamplona, Reinald, Victor, Victor M., Jové, Mariona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831788/
https://www.ncbi.nlm.nih.gov/pubmed/31690730
http://dx.doi.org/10.1038/s41598-019-52263-w