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Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia

Hypoxia and acidity provide microenvironment for selection under evolutionary pressure and proliferation in cancer cells. Carbonic anhydrases (CAs) are a superfamily of metalloenzymes present in all life kingdoms, equilibrating the reactions among CO(2), bicarbonate and H(+). CA9, a membrane-associa...

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Detalles Bibliográficos
Autores principales: Li, Zan, Jiang, Li, Chew, Shan Hwu, Hirayama, Tasuku, Sekido, Yoshitaka, Toyokuni, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831888/
https://www.ncbi.nlm.nih.gov/pubmed/31442913
http://dx.doi.org/10.1016/j.redox.2019.101297