Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2

Exaggerated signaling by vascular endothelial growth factor (VEGF)‐A and its receptor, VEGFR2, in pathologies results in poor vessel function. Still, pharmacological suppression of VEGFA/VEGFR2 may aggravate disease. Delineating VEGFR2 signaling in vivo provides strategies for suppression of specifi...

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Detalles Bibliográficos
Autores principales: Testini, Chiara, Smith, Ross O, Jin, Yi, Martinsson, Pernilla, Sun, Ying, Hedlund, Marie, Sáinz‐Jaspeado, Miguel, Shibuya, Masabumi, Hellström, Mats, Claesson‐Welsh, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832004/
https://www.ncbi.nlm.nih.gov/pubmed/31545012
http://dx.doi.org/10.15252/embr.201947845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832004/
https://www.ncbi.nlm.nih.gov/pubmed/31545012
http://dx.doi.org/10.15252/embr.201947845

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