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Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2
Exaggerated signaling by vascular endothelial growth factor (VEGF)‐A and its receptor, VEGFR2, in pathologies results in poor vessel function. Still, pharmacological suppression of VEGFA/VEGFR2 may aggravate disease. Delineating VEGFR2 signaling in vivo provides strategies for suppression of specifi...
Autores principales: | Testini, Chiara, Smith, Ross O, Jin, Yi, Martinsson, Pernilla, Sun, Ying, Hedlund, Marie, Sáinz‐Jaspeado, Miguel, Shibuya, Masabumi, Hellström, Mats, Claesson‐Welsh, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832004/ https://www.ncbi.nlm.nih.gov/pubmed/31545012 http://dx.doi.org/10.15252/embr.201947845 |
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