Synthesis and Cyclooxygenase Inhibition of Sulfonamide-Substituted (Dihydro)Pyrrolo[3,2,1-hi]indoles and Their Potential Prodrugs

Non-invasive imaging of cyclooxygenase-2 (COX-2) by radiolabeled ligands is attractive for the diagnosis of cancer, and novel highly affine leads with optimized pharmacokinetic profile are of great interest for future developments. Recent findings have shown that methylsulfonyl-substituted (dihydro)...

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Detalles Bibliográficos
Autores principales: Laube, Markus, Gassner, Cemena, Kniess, Torsten, Pietzsch, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832141/
https://www.ncbi.nlm.nih.gov/pubmed/31652609
http://dx.doi.org/10.3390/molecules24203807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832141/
https://www.ncbi.nlm.nih.gov/pubmed/31652609
http://dx.doi.org/10.3390/molecules24203807

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