Iduronate-2-Sulfatase-Regulated Dermatan Sulfate Levels Potentiate the Invasion of Breast Cancer Epithelia through Collagen Matrix

Cancer epithelia show elevation in levels of sulfated proteoglycans including dermatan sulfates (DS). The effect of increased DS on cancer cell behavior is still unclear. We hypothesized that decreased expression of the enzyme Iduronate-2-sulfatase (IDS) can lead to increased DS levels, which would...

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Detalles Bibliográficos
Autores principales: Singh, Vishal, Jha, Keshav Kumar, M, Jyothsna K., Kumar, Rekha V., Raghunathan, Varun, Bhat, Ramray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832158/
https://www.ncbi.nlm.nih.gov/pubmed/31574977
http://dx.doi.org/10.3390/jcm8101562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832158/
https://www.ncbi.nlm.nih.gov/pubmed/31574977
http://dx.doi.org/10.3390/jcm8101562

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