HU-671, a Novel Oleoyl Serine Derivative, Exhibits Enhanced Efficacy in Reversing Ovariectomy-Induced Osteoporosis and Bone Marrow Adiposity

Oleoyl serine (OS), an endogenous fatty acyl amide (FAA) found in bone, has been shown to have an anti-osteoporotic effect. OS, being an amide, can be hydrolyzed in the body by amidases. Hindering its amide bond by introducing adjacent substituents has been demonstrated as a successful method for pr...

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Detalles Bibliográficos
Autores principales: Baraghithy, Saja, Smoum, Reem, Attar-Namdar, Malka, Mechoulam, Raphael, Bab, Itai, Tam, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832161/
https://www.ncbi.nlm.nih.gov/pubmed/31623098
http://dx.doi.org/10.3390/molecules24203719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832161/
https://www.ncbi.nlm.nih.gov/pubmed/31623098
http://dx.doi.org/10.3390/molecules24203719

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