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Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy

Human A(3) adenosine receptor hA(3)AR has been implicated in gastrointestinal cancer, where its cellular expression has been found increased, thus suggesting its potential as a molecular target for novel anticancer compounds. Observation made in our previous work indicated the importance of the carb...

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Detalles Bibliográficos
Autores principales: Tan, Aaron, Babak, Maria V., Venkatesan, Gopalakrishnan, Lim, Clarissa, Klotz, Karl-Norbert, Herr, Deron Raymond, Cheong, Siew Lee, Federico, Stephanie, Spalluto, Giampiero, Ong, Wei-Yi, Chen, Yu Zong, Loo, Jason Siau Ee, Pastorin, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832257/
https://www.ncbi.nlm.nih.gov/pubmed/31614517
http://dx.doi.org/10.3390/molecules24203661