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Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues

Cross-metathesis (CM) and Keck asymmetric allylation, which allows access to defined stereochemistry of a remote side chain hydroxyl group, are the key steps in a versatile synthesis of broussonetine M (3) from the d-arabinose-derived cyclic nitrone 14. By a similar strategy, ent-broussonetine M (en...

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Detalles Bibliográficos
Autores principales: Wu, Qing-Kun, Kinami, Kyoko, Kato, Atsushi, Li, Yi-Xian, Jia, Yue-Mei, Fleet, George W. J., Yu, Chu-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832352/
https://www.ncbi.nlm.nih.gov/pubmed/31619020
http://dx.doi.org/10.3390/molecules24203712