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Concise and Gram-Scale Total Synthesis of Lansiumamides A and B and Alatamide

The total synthesis of potent anti-obesity lansiumamide B was accomplished in four steps using commercially available materials. The synthetic strategy, featured with copper-catalyzed Buchwald coupling, is concise, convergent, practical and can be carried out on a one-gram scale. This approach could...

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Detalles Bibliográficos
Autores principales: Lin, Ran, Lin, Xi, Su, Qian, Guo, Binbin, Huang, Yanqin, Ouyang, Ming-An, Song, Liyan, Xu, Huiyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832413/
https://www.ncbi.nlm.nih.gov/pubmed/31635023
http://dx.doi.org/10.3390/molecules24203764