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Plasma pS129-α-Synuclein Is a Surrogate Biofluid Marker of Motor Severity and Progression in Parkinson’s Disease

Phosphorylated α-synuclein accounts for more than 90% of α-synuclein found in Lewy bodies of Parkinson’s disease (PD). We aimed to examine whether plasma Ser129-phosphorylated α-synuclein (pS129-α-synuclein) is a surrogate marker of PD progression. This prospective study enrolled 170 participants (1...

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Detalles Bibliográficos
Autores principales: Lin, Chin-Hsien, Liu, Huei-Chun, Yang, Shieh-Yueh, Yang, Kai-Chien, Wu, Chau-Chung, Chiu, Ming-Jang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832465/
https://www.ncbi.nlm.nih.gov/pubmed/31623323
http://dx.doi.org/10.3390/jcm8101601