NT5E/CD73 as Correlative Factor of Patient Survival and Natural Killer Cell Infiltration in Glioblastoma

CD73, a cell-surface protein encoded by the gene NT5E, is overexpressed in glioblastoma (GBM), where it contributes to the tumor’s pathophysiology via the generation of immunosuppressive adenosine. Adenosinergic signaling, in turn, drives immunosuppression of natural killer (NK) cells through metabo...

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Detalles Bibliográficos
Autores principales: Wang, Jiao, Matosevic, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832588/
https://www.ncbi.nlm.nih.gov/pubmed/31547570
http://dx.doi.org/10.3390/jcm8101526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832588/
https://www.ncbi.nlm.nih.gov/pubmed/31547570
http://dx.doi.org/10.3390/jcm8101526

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