Sa12b Peptide from Solitary Wasp Inhibits ASIC Currents in Rat Dorsal Root Ganglion Neurons

In this work, we evaluate the effect of two peptides Sa12b (EDVDHVFLRF) and Sh5b (DVDHVFLRF-NH(2)) on Acid-Sensing Ion Channels (ASIC). These peptides were purified from the venom of solitary wasps Sphex argentatus argentatus and Isodontia harmandi, respectively. Voltage clamp recordings of ASIC cur...

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Detalles Bibliográficos
Autores principales: Hernández, Carmen, Konno, Katsuhiro, Salceda, Emilio, Vega, Rosario, Zaharenko, André Junqueira, Soto, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832649/
https://www.ncbi.nlm.nih.gov/pubmed/31658776
http://dx.doi.org/10.3390/toxins11100585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832649/
https://www.ncbi.nlm.nih.gov/pubmed/31658776
http://dx.doi.org/10.3390/toxins11100585

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