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Sa12b Peptide from Solitary Wasp Inhibits ASIC Currents in Rat Dorsal Root Ganglion Neurons

In this work, we evaluate the effect of two peptides Sa12b (EDVDHVFLRF) and Sh5b (DVDHVFLRF-NH(2)) on Acid-Sensing Ion Channels (ASIC). These peptides were purified from the venom of solitary wasps Sphex argentatus argentatus and Isodontia harmandi, respectively. Voltage clamp recordings of ASIC cur...

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Detalles Bibliográficos
Autores principales:	Hernández, Carmen, Konno, Katsuhiro, Salceda, Emilio, Vega, Rosario, Zaharenko, André Junqueira, Soto, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832649/ https://www.ncbi.nlm.nih.gov/pubmed/31658776 http://dx.doi.org/10.3390/toxins11100585

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