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Synthesis of 9-Hydroxystearic Acid Derivatives and Their Antiproliferative Activity on HT 29 Cancer Cells

9-Hydroxystearic acid (9-HSA) is an endogenous cellular lipid that possesses antiproliferative and selective effects against cancer cells. A series of derivatives were synthesized in order to investigate the effect of the substituent in position 9 and on the methyl ester functionality on the biologi...

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Detalles Bibliográficos
Autores principales: Calonghi, Natalia, Boga, Carla, Telese, Dario, Bordoni, Silvia, Sartor, Giorgio, Torsello, Chiara, Micheletti, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832665/
https://www.ncbi.nlm.nih.gov/pubmed/31619025
http://dx.doi.org/10.3390/molecules24203714