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Sequential MCR via Staudinger/Aza-Wittig versus Cycloaddition Reaction to Access Diversely Functionalized 1-Amino-1H-Imidazole-2(3H)-Thiones

A multicomponent reaction (MCR) strategy, alternative to the known cycloaddition reaction, towards variously substituted 1-amino-1H-imidazole-2(3H)-thione derivatives has been successfully developed. The novel approach involves α-halohydrazones whose azidation process followed by tandem Staudinger/a...

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Detalles Bibliográficos
Autores principales: Ciccolini, Cecilia, Mari, Giacomo, Favi, Gianfranco, Mantellini, Fabio, De Crescentini, Lucia, Santeusanio, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832714/
https://www.ncbi.nlm.nih.gov/pubmed/31640206
http://dx.doi.org/10.3390/molecules24203785