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Dynamics of Phenotypic Heterogeneity Associated with EMT and Stemness during Cancer Progression

Genetic and phenotypic heterogeneity contribute to the generation of diverse tumor cell populations, thus enhancing cancer aggressiveness and therapy resistance. Compared to genetic heterogeneity, a consequence of mutational events, phenotypic heterogeneity arises from dynamic, reversible cell state...

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Detalhes bibliográficos
Autores principales: Jolly, Mohit Kumar, Celià-Terrassa, Toni
Formato: Online Artigo Texto
Idioma:English
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832750/
https://www.ncbi.nlm.nih.gov/pubmed/31557977
http://dx.doi.org/10.3390/jcm8101542