Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine–Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors

A series of novel thienopyridines and pyridothienoquinolines (3a,b–14) was synthesized, starting with 2-thioxo-1,2-dihydropyridine-3-carbonitriles 1a and 1b. All compounds were evaluated for their in vitro antimicrobial activity against six bacterial strains. Compounds 3a,b, 4a, 5b, 6a,b, 7a, 9b, 12...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohi El-Deen, Eman M., Abd El-Meguid, Eman A., Hasabelnaby, Sherifa, Karam, Eman A., Nossier, Eman S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832920/
https://www.ncbi.nlm.nih.gov/pubmed/31658631
http://dx.doi.org/10.3390/molecules24203650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832920/
https://www.ncbi.nlm.nih.gov/pubmed/31658631
http://dx.doi.org/10.3390/molecules24203650

Ejemplares similares