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Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine–Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors

A series of novel thienopyridines and pyridothienoquinolines (3a,b–14) was synthesized, starting with 2-thioxo-1,2-dihydropyridine-3-carbonitriles 1a and 1b. All compounds were evaluated for their in vitro antimicrobial activity against six bacterial strains. Compounds 3a,b, 4a, 5b, 6a,b, 7a, 9b, 12...

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Detalles Bibliográficos
Autores principales:	Mohi El-Deen, Eman M., Abd El-Meguid, Eman A., Hasabelnaby, Sherifa, Karam, Eman A., Nossier, Eman S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832920/ https://www.ncbi.nlm.nih.gov/pubmed/31658631 http://dx.doi.org/10.3390/molecules24203650

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