Design and Selection of Novel C1s Inhibitors by In Silico and In Vitro Approaches

The complement system is associated with various diseases such as inflammation or auto-immune diseases. Complement-targeted drugs could provide novel therapeutic intervention against the above diseases. C1s, a serine protease, plays an important role in the CS and could be an attractive target since...

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Detalles Bibliográficos
Autores principales: Szilágyi, Katalin, Hajdú, István, Flachner, Beáta, Lőrincz, Zsolt, Balczer, Júlia, Gál, Péter, Závodszky, Péter, Pirli, Chiara, Balogh, Balázs, Mándity, István M., Cseh, Sándor, Dormán, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832932/
https://www.ncbi.nlm.nih.gov/pubmed/31600984
http://dx.doi.org/10.3390/molecules24203641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832932/
https://www.ncbi.nlm.nih.gov/pubmed/31600984
http://dx.doi.org/10.3390/molecules24203641

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