Detection of Several Homologous MicroRNAs by a Single Smart Probe System Consisting of Linear Nucleic Acid Blockers

We report a universal smart probe (SP) that is capable of detecting several homologous let-7 microRNAs (miRNAs). While the SP is complementary to let-7a, and therefore, strongly binds to this target, due to sequence homology, the SP also has equal propensity to non-specifically hybridize with let-7b...

Descripción completa

Detalles Bibliográficos
Autores principales: Oladepo, Sulayman A., Yusuf, Basiru O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832958/
https://www.ncbi.nlm.nih.gov/pubmed/31615053
http://dx.doi.org/10.3390/molecules24203691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832958/
https://www.ncbi.nlm.nih.gov/pubmed/31615053
http://dx.doi.org/10.3390/molecules24203691

Ejemplares similares