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Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment

Gene therapy for osteoarthritis offers powerful, long-lasting tools that are well adapted to treat such a slow, progressive disorder, especially those therapies based on the clinically adapted recombinant adeno-associated viral (rAAV) vectors. Here, we examined the ability of an rAAV construct carry...

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Detalles Bibliográficos
Autores principales: Daniels, Oliver, Frisch, Janina, Venkatesan, Jagadeesh K., Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832991/
https://www.ncbi.nlm.nih.gov/pubmed/31591319
http://dx.doi.org/10.3390/jcm8101637