Cargando…
Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment
Gene therapy for osteoarthritis offers powerful, long-lasting tools that are well adapted to treat such a slow, progressive disorder, especially those therapies based on the clinically adapted recombinant adeno-associated viral (rAAV) vectors. Here, we examined the ability of an rAAV construct carry...
Autores principales: | Daniels, Oliver, Frisch, Janina, Venkatesan, Jagadeesh K., Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832991/ https://www.ncbi.nlm.nih.gov/pubmed/31591319 http://dx.doi.org/10.3390/jcm8101637 |
Ejemplares similares
-
rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ
por: Venkatesan, Jagadeesh K, et al.
Publicado: (2013) -
Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors
por: Venkatesan, Jagadeesh K., et al.
Publicado: (2017) -
Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates
por: Tao, Ke, et al.
Publicado: (2017) -
TGF‐β gene transfer and overexpression via
rAAV vectors stimulates chondrogenic events in human bone marrow aspirates
por: Frisch, Janina, et al.
Publicado: (2016) -
Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells
por: Tao, Ke, et al.
Publicado: (2016)