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Synthesis of Trichodermin Derivatives and Their Antimicrobial and Cytotoxic Activities

Trichothecene mycotoxins are recognized as highly bioactive compounds that can be used in the design of new useful bioactive molecules. In Trichoderma brevicompactum, the first specific step in trichothecene biosynthesis is carried out by a terpene cyclase, trichodiene synthase, that catalyzes the c...

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Detalles Bibliográficos
Autores principales: Barúa, Javier E., de la Cruz, Mercedes, de Pedro, Nuria, Cautain, Bastien, Hermosa, Rosa, Cardoza, Rosa E., Gutiérrez, Santiago, Monte, Enrique, Vicente, Francisca, Collado, Isidro G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833013/
https://www.ncbi.nlm.nih.gov/pubmed/31652666
http://dx.doi.org/10.3390/molecules24203811