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Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages

Activation of the transcription factor liver X receptor (LXR) has beneficial effects on macrophage lipid metabolism and inflammation, making it a potential candidate for therapeutic targeting in cardiometabolic disease. While small molecule delivery via nanomedicine has promising applications for a...

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Detalles Bibliográficos
Autores principales: Smith, Tyler K. T., Kahiel, Zaina, LeBlond, Nicholas D., Ghorbani, Peyman, Farah, Eliya, Al-Awosi, Refel, Cote, Marceline, Gadde, Suresh, Fullerton, Morgan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833070/
https://www.ncbi.nlm.nih.gov/pubmed/31635211
http://dx.doi.org/10.3390/molecules24203751