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Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages
Activation of the transcription factor liver X receptor (LXR) has beneficial effects on macrophage lipid metabolism and inflammation, making it a potential candidate for therapeutic targeting in cardiometabolic disease. While small molecule delivery via nanomedicine has promising applications for a...
Autores principales: | Smith, Tyler K. T., Kahiel, Zaina, LeBlond, Nicholas D., Ghorbani, Peyman, Farah, Eliya, Al-Awosi, Refel, Cote, Marceline, Gadde, Suresh, Fullerton, Morgan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833070/ https://www.ncbi.nlm.nih.gov/pubmed/31635211 http://dx.doi.org/10.3390/molecules24203751 |
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