Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns

Background: Besides its well-known functions in hemostasis, thrombin plays a role in various non-hemostatic biological and pathophysiologic processes. We examined the potential of thrombin to promote premature atrial endothelial cells (ECs) senescence. Methods and Results: Primary ECs were isolated...

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Detalles Bibliográficos
Autores principales: Hasan, Hira, Park, Sin-Hee, Auger, Cyril, Belcastro, Eugenia, Matsushita, Kensuke, Marchandot, Benjamin, Lee, Hyun-Ho, Qureshi, Abdul Wahid, Kauffenstein, Gilles, Ohlmann, Patrick, Schini-Kerth, Valérie B, Jesel, Laurence, Morel, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833093/
https://www.ncbi.nlm.nih.gov/pubmed/31581517
http://dx.doi.org/10.3390/jcm8101570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833093/
https://www.ncbi.nlm.nih.gov/pubmed/31581517
http://dx.doi.org/10.3390/jcm8101570

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