Cargando…

Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns

Background: Besides its well-known functions in hemostasis, thrombin plays a role in various non-hemostatic biological and pathophysiologic processes. We examined the potential of thrombin to promote premature atrial endothelial cells (ECs) senescence. Methods and Results: Primary ECs were isolated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hasan, Hira, Park, Sin-Hee, Auger, Cyril, Belcastro, Eugenia, Matsushita, Kensuke, Marchandot, Benjamin, Lee, Hyun-Ho, Qureshi, Abdul Wahid, Kauffenstein, Gilles, Ohlmann, Patrick, Schini-Kerth, Valérie B, Jesel, Laurence, Morel, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833093/ https://www.ncbi.nlm.nih.gov/pubmed/31581517 http://dx.doi.org/10.3390/jcm8101570

Ejemplares similares

Angiotensin II-induced upregulation of SGLT1 and 2 contributes to human microparticle‐stimulated endothelial senescence and dysfunction: protective effect of gliflozins
por: Park, Sin-Hee, et al.
Publicado: (2021)

Atrial Fibrillation Progression Is Associated with Cell Senescence Burden as Determined by p53 and p16 Expression
por: Jesel, Laurence, et al.
Publicado: (2019)

COVID-19 Related Coagulopathy: A Distinct Entity?
por: Marchandot, Benjamin, et al.
Publicado: (2020)

Angiotensin II‐induced redox‐sensitive SGLT1 and 2 expression promotes high glucose‐induced endothelial cell senescence
por: Khemais‐Benkhiat, Sonia, et al.
Publicado: (2019)

Impact of COVID-19 on the Cardiovascular System: A Review
por: Matsushita, Kensuke, et al.
Publicado: (2020)

Determinants and treatments of heart failure after transcatheter aortic valve implantation: moving up a notch
por: Matsushita, Kensuke, et al.
Publicado: (2023)

Empagliflozin improved systolic blood pressure, endothelial dysfunction and heart remodeling in the metabolic syndrome ZSF1 rat
por: Park, Sin-Hee, et al.
Publicado: (2020)

Grape-Derived Polyphenols Improve Aging-Related Endothelial Dysfunction in Rat Mesenteric Artery: Role of Oxidative Stress and the Angiotensin System
por: Idris Khodja, Noureddine, et al.
Publicado: (2012)

Impact of Covid-19 infection in high-risk coronary patients
por: Carmona, A., et al.
Publicado: (2021)

Thromboprophylaxis: balancing evidence and experience during the COVID-19 pandemic
por: Marchandot, Benjamin, et al.
Publicado: (2020)

Clinical features of patients with acute coronary syndrome during the COVID-19 pandemic
por: Matsushita, Kensuke, et al.
Publicado: (2020)

Microparticles in COVID-19 as a link between lung injury extension and thrombosis
por: Morel, Olivier, et al.
Publicado: (2021)

Impact of gender on left atrial low-voltage zones in patients with persistent atrial fibrillation: results of a voltage-guided ablation
por: Marzak, Halim, et al.
Publicado: (2023)

Probiotics (VSL#3) Prevent Endothelial Dysfunction in Rats with Portal Hypertension: Role of the Angiotensin System
por: Rashid, Sherzad K., et al.
Publicado: (2014)

Bedside Renal Doppler Ultrasonography and Acute Kidney Injury after TAVR
por: Peillex, Marilou, et al.
Publicado: (2020)

Transient endothelial injury and release of lupus anticoagulant in COVID-19
por: Trimaille, Antonin, et al.
Publicado: (2021)

Baseline mean platelet volume is a strong predictor of major and life-threatening bleedings after transcatheter aortic valve replacement
por: Trimaille, Antonin, et al.
Publicado: (2021)

Impact of Antithrombotic Regimen and Platelet Inhibition Extent on Leaflet Thrombosis Detected by Cardiac MDCT after Transcatheter Aortic Valve Replacement
por: Jimenez, Charline, et al.
Publicado: (2019)

Impact of Incomplete Coronary Revascularization on Late Ischemic and Bleeding Events after Transcatheter Aortic Valve Replacement
por: Carmona, Adrien, et al.
Publicado: (2020)

Increased susceptibility to SARS‐CoV‐2 infection in patients with reduced left ventricular ejection fraction
por: Matsushita, Kensuke, et al.
Publicado: (2020)

Electrocardiographic Strain Pattern Is a Major Determinant of Rehospitalization for Heart Failure After Transcatheter Aortic Valve Replacement
por: Heger, Joé, et al.
Publicado: (2021)

Acute Pulmonary Embolism in Patients with and without COVID-19
por: Trimaille, Antonin, et al.
Publicado: (2021)

Combination of Primary Hemostatic Disorders and Atrial Fibrillation Increases Bleeding Events Following Transcatheter Aortic Valve Replacement
por: Matsushita, Kensuke, et al.
Publicado: (2023)

Long-term cardiovascular complications following sepsis: is senescence the missing link?
por: Merdji, Hamid, et al.
Publicado: (2021)

Transient endothelial injury and release of lupus anticoagulant in COVID-19
por: Trimaille, A., et al.
Publicado: (2022)

Acute kidney injury and acute kidney recovery following Transcatheter Aortic Valve Replacement
por: Peillex, Marilou, et al.
Publicado: (2021)

Endometriosis and cardiovascular disease
por: Marchandot, Benjamin, et al.
Publicado: (2022)

Impact of Primary Hemostasis Disorders on Late Major Bleeding Events among Anticoagulated Atrial Fibrillation Patients Treated by TAVR
por: Dietrich, Laurent, et al.
Publicado: (2021)

Assessment of Renal Dysfunction Improves the Simplified Pulmonary Embolism Severity Index (sPESI) for Risk Stratification in Patients with Acute Pulmonary Embolism
por: Trimaille, Antonin, et al.
Publicado: (2019)

Redox-Sensitive Induction of Src/PI3-kinase/Akt and MAPKs Pathways Activate eNOS in Response to EPA:DHA 6:1
por: Zgheel, Faraj, et al.
Publicado: (2014)

The Effect of Transoesophageal Echocardiography on Treatment Change in a High-Volume Stroke Unit
por: Siegel, Camille, et al.
Publicado: (2021)

Antiplatelet Therapy in ACS Patients: Comparing Appropriate P2Y12 Inhibition by Clopidogrel to the Use of New P2Y12 Inhibitors
por: Ristorto, Jessica, et al.
Publicado: (2018)

Adenylate Cyclase Type III Is Not a Ubiquitous Marker for All Primary Cilia during Development
por: Antal, Maria Cristina, et al.
Publicado: (2017)

Impact of residual inflammation on myocardial recovery and cardiovascular outcome in Takotsubo patients
por: Lachmet‐Thebaud, Lucie, et al.
Publicado: (2020)

Prognostic Value of Incomplete Revascularization after Percutaneous Coronary Intervention Following Acute Coronary Syndrome: Focus on CKD Patients
por: Cardi, Thomas, et al.
Publicado: (2019)

Significance of neutrophil microparticles in ischaemia‐reperfusion: Pro‐inflammatory effectors of endothelial senescence and vascular dysfunction
por: El Habhab, Ali, et al.
Publicado: (2020)

Risk and Severity of COVID-19 and ABO Blood Group in Transcatheter Aortic Valve Patients
por: Kibler, Marion, et al.
Publicado: (2020)

ChatGPT: the next frontier in academic writing for cardiologists or a pandora’s box of ethical dilemmas
por: Marchandot, Benjamin, et al.
Publicado: (2023)

Short-Term Effects of Air Pollution on Coronary Events in Strasbourg, France—Importance of Seasonal Variations
por: Vaudrey, Baptiste, et al.
Publicado: (2020)

Impact of Opioid Analgesia and Inhalation Sedation Kalinox on Pain and Radial Artery Spasm during Transradial Coronary Angiography
por: Birgy, Caroline, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ebnulpgmi8m4dm3g3kaof4e7qh