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Barium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels

BACKGROUND: Local injection of BaCl(2) is an established model of acute injury to study the regeneration of skeletal muscle. However, the mechanism by which BaCl(2) causes muscle injury is unresolved. Because Ba(2+) inhibits K(+) channels, we hypothesized that BaCl(2) induces myofiber depolarization...

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Detalles Bibliográficos
Autores principales: Morton, Aaron B., Norton, Charles E., Jacobsen, Nicole L., Fernando, Charmain A., Cornelison, D. D. W., Segal, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833148/
https://www.ncbi.nlm.nih.gov/pubmed/31694693
http://dx.doi.org/10.1186/s13395-019-0213-2