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Investigation of the methylerythritol 4-phosphate pathway for microbial terpenoid production through metabolic control analysis

BACKGROUND: Terpenoids are of high interest as chemical building blocks and pharmaceuticals. In microbes, terpenoids can be synthesized via the methylerythritol phosphate (MEP) or mevalonate (MVA) pathways. Although the MEP pathway has a higher theoretical yield, metabolic engineering has met with l...

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Detalles Bibliográficos
Autores principales: Volke, Daniel Christoph, Rohwer, Johann, Fischer, Rainer, Jennewein, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833178/
https://www.ncbi.nlm.nih.gov/pubmed/31690314
http://dx.doi.org/10.1186/s12934-019-1235-5