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Quality control of imbalanced mass spectra from isotopic labeling experiments

BACKGROUND: Mass spectra are usually acquired from the Liquid Chromatography-Mass Spectrometry (LC-MS) analysis for isotope labeled proteomics experiments. In such experiments, the mass profiles of labeled (heavy) and unlabeled (light) peptide pairs are represented by isotope clusters (2D or 3D) tha...

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Detalles Bibliográficos
Autores principales: Li, Tianjun, Chen, Long, Gan, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833298/
https://www.ncbi.nlm.nih.gov/pubmed/31694522
http://dx.doi.org/10.1186/s12859-019-3170-1