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Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief

We have previously reported that the microtubule-associated collapsin response mediator protein 2 (CRMP2) is necessary for the expression of chronic pain. CRMP2 achieves this control of nociceptive signaling by virtue of its ability to regulate voltage-gated calcium and sodium channels. To date, how...

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Detalles Bibliográficos
Autores principales: Moutal, Aubin, Shan, Zhiming, Miranda, Victor G., François-Moutal, Liberty, Madura, Cynthia L., Khanna, May, Khanna, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833970/
https://www.ncbi.nlm.nih.gov/pubmed/31680630
http://dx.doi.org/10.1080/19336950.2019.1684608