Thrombin Upregulates PAI-1 and Mesothelial–Mesenchymal Transition Through PAR-1 and Contributes to Tuberculous Pleural Fibrosis

Thrombin is an essential procoagulant and profibrotic mediator. However, its implication in tuberculous pleural effusion (TBPE) remains unknown. The effusion thrombin and plasminogen activator inhibitor-1 (PAI-1) levels were measured among transudative pleural effusion (TPE, n = 22) and TBPE (n = 24...

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Detalles Bibliográficos
Autores principales: Hsieh, Cheng-Ying, Sheu, Joen-Rong, Yang, Chih-Hao, Chen, Wei-Lin, Tsai, Jie-Heng, Chung, Chi-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834128/
https://www.ncbi.nlm.nih.gov/pubmed/31614900
http://dx.doi.org/10.3390/ijms20205076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834128/
https://www.ncbi.nlm.nih.gov/pubmed/31614900
http://dx.doi.org/10.3390/ijms20205076

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