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Effect of Single Amino Acid Substitutions by Asn and Gln on Aggregation Properties of Bence-Jones Protein BIF

The nature of renal amyloidosis involving Bence-Jones proteins in multiple myeloma is still unclear. The development of amyloidosis in neurodegenerative diseases is often associated with a high content of asparagine and glutamine residues in proteins forming amyloid deposits. To estimate the influen...

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Detalles Bibliográficos
Autores principales: Timchenko, Maria, Abdullatypov, Azat, Kihara, Hiroshi, Timchenko, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834151/
https://www.ncbi.nlm.nih.gov/pubmed/31635169
http://dx.doi.org/10.3390/ijms20205197