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Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro

The blood-brain barrier (BBB), composed of brain microvascular endothelial cells (BMEC) that are tightly linked by tight junction (TJ) proteins, restricts the movement of molecules between the periphery and the central nervous system. Elevated systemic levels of neutrophils have been detected in pat...

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Detalles Bibliográficos
Autores principales: Ajikumar, Anjana, Long, Merete B., Heath, Paul R., Wharton, Stephen B., Ince, Paul G., Ridger, Victoria C., Simpson, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834153/
https://www.ncbi.nlm.nih.gov/pubmed/31652502
http://dx.doi.org/10.3390/ijms20205227