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Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides

The process of pre-mRNA splicing is a common and fundamental step in the expression of most human genes. Alternative splicing, whereby different splice motifs and sites are recognised in a developmental and/or tissue-specific manner, contributes to genetic plasticity and diversity of gene expression...

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Detalles Bibliográficos
Autores principales: Aung-Htut, May T., McIntosh, Craig S., Ham, Kristin A., Pitout, Ianthe L., Flynn, Loren L., Greer, Kane, Fletcher, Sue, Wilton, Steve D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834167/
https://www.ncbi.nlm.nih.gov/pubmed/31614438
http://dx.doi.org/10.3390/ijms20205030