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In Silico Insights towards the Identification of NLRP3 Druggable Hot Spots

NLRP3 (NOD-like receptor family, pyrin domain-containing protein 3) activation has been linked to several chronic pathologies, including atherosclerosis, type-II diabetes, fibrosis, rheumatoid arthritis, and Alzheimer’s disease. Therefore, NLRP3 represents an appealing target for the development of...

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Detalles Bibliográficos
Autores principales: Mekni, Nedra, De Rosa, Maria, Cipollina, Chiara, Gulotta, Maria Rita, De Simone, Giada, Lombino, Jessica, Padova, Alessandro, Perricone, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834175/
https://www.ncbi.nlm.nih.gov/pubmed/31600880
http://dx.doi.org/10.3390/ijms20204974