Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes

The distribution of DNA damage and repair is considered to occur heterogeneously across the genome. However, commonly available techniques, such as the alkaline comet assay or HPLC-MS/MS, measure global genome levels of DNA damage, and do not reflect potentially significant events occurring at the g...

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Detalles Bibliográficos
Autores principales: Alhegaili, Alaa S., Ji, Yunhee, Sylvius, Nicolas, Blades, Matthew J., Karbaschi, Mahsa, Tempest, Helen G., Jones, George D. D., Cooke, Marcus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834194/
https://www.ncbi.nlm.nih.gov/pubmed/31618917
http://dx.doi.org/10.3390/ijms20205112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834194/
https://www.ncbi.nlm.nih.gov/pubmed/31618917
http://dx.doi.org/10.3390/ijms20205112

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