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Prediction of PD-L1 inhibition effects for HIV-infected individuals

The novel therapies with immune checkpoint inhibitors hold great promises for patients with chronic virus infections and cancers. This is based mainly on the partial reversal of the exhausted phenotype of antigen-specific cytotoxic CD8 T cells (CTL). Recently, we have shown that the restoration of H...

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Detalles Bibliográficos
Autores principales: Zheltkova, Valerya, Argilaguet, Jordi, Peligero, Cristina, Bocharov, Gennady, Meyerhans, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834253/
https://www.ncbi.nlm.nih.gov/pubmed/31693657
http://dx.doi.org/10.1371/journal.pcbi.1007401